Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ GGACK
An irreversible inhibitor of urokinase (IC50 1 μM) and Factor Xa.
MilliporeSigma™ Calbiochem™ Anaphase-Promoting Complex Inhibitor Negative Control, AAME
The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.
MilliporeSigma™ Calbiochem™ MLKL Inhibitor, Necrosulfonamide
MLKL Inhibitor, Necrosulfonamide, CAS 432531-71-0, is a cell-permeable inhibitor that covalently modifies Cys88 and blocks human MLKL adaptor function.
MilliporeSigma™ Calbiochem™ Eicosapentaenoic Acid
Cell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity.
MilliporeSigma™ Calbiochem™ Chk2 Inhibitor, PV1019
The Chk2 Inhibitor, PV1019 controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ IKK-2 Inhibitor IV
The IKK-2 Inhibitor IV, also referenced under CAS 507475-17-4, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ PD 169316
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM).
MilliporeSigma™ Calbiochem™ BCL6 Inhibitor, 79-6
The BCL6 Inhibitor, 79-6 controls the biological activity of BCL6. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Hydroxychloroquine Sulfate
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC50 = 30 μM).
MilliporeSigma™ Calbiochem™ AG 1024
A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity.
MilliporeSigma™ Calbiochem™ Calpain Substrate II, Fluorogenic
Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2.
MilliporeSigma™ Calbiochem™ CMP-Sialic Acid, Disodium Salt InSolution™
A 25 mM (10 mg/608 μL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt in H2O.
MilliporeSigma™ Calbiochem™ (-)-Blebbistatin
The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Potassium Salt
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
MilliporeSigma™ Calbiochem™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC50 = 58 nM, 210 nM, & 2.12 μM for Akt1, Akt2, and Akt3, respectively).